First case in Central China! 3D printing titanium alloy "mandible" implanted in the face of 74-year-old man

Category： Company News

Pulished Time：2019-05-01

On April 29, Professor Jia Jun, deputy director of the Department of Oral and Maxillofacial Head and Neck Tumor Surgery, Wuhan University Stomatological Hospital, and his team studied and designed the 3D printed titanium alloy "mandible" successfully implanted into the patient's face. The patient recovered well after the operation and was ready to be discharged tomorrow. At the same time, it also marks the successful implementation of the first 3D printed titanium alloy "mandible" transplantation in central China.
Li Lao, 74, of Tongcheng County, Xianning City, was diagnosed with right lower gingival cell carcinoma in 2017 at Wuda Stomatological Hospital and underwent partial resection of the right mandible. After the operation, Mr. Li's spirit, appetite, and sleep were good, but the right side of the face collapsed, long-term missing teeth, unable to chew normally, seriously affecting eating, making him feel very inconvenient. A year and a half later, Li Lao, accompanied by his son, went to Wuda Stomatological Hospital to request the repair of the right mandibular defect.
华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

Before surgery
"Although the elderly Li Lao has strong bones, if he is taken from the body bone graft, the surgical trauma will be greater for him, and the recovery speed of the body will be slower than that of the young and middle-aged." Professor Jia Jun said. Considering Li Lao's age and physical tolerance, Professor Jia Jun communicated with the patient to see if he would try to use the national key research and development project-3D printing titanium alloy, which his team participated in, to repair the mandible.
华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

3D printed titanium mandible
In recent years, the international and domestic media have only reported a few cases of 3D printing titanium alloy prosthesis transplantation, which also has certain risks. Faced with all kinds of uncertain factors, Li Lao and his son still discussed and hoped that they could be repaired. "Although my father is old, he still wants him to live a good old age as a child. Once again, we also believe in the country's developed medical technology." Lee's son said.
The 3D printed titanium alloy "mandible" designed by Professor Jia Jun and his team for nearly a year was transplanted to the defect of Li Lao's right mandible on April 22 this year. The operation took only 2 hours. The team's designers include doctors in oral tumor surgery, experts in mechanical analysis, software analysis engineers, 3D printing engineers, etc. to escort Li Lao's titanium alloy "mandible" from all aspects of prosthesis shape, structure, mechanical strength, etc. After a week of postoperative recovery, the patient was discharged from the hospital tomorrow with stitches removed.
华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

华中首例！3D打印钛合金“下颌骨”植入74岁老人面部

Jia Jun pointed out that because the application of titanium alloy in the human body has been relatively mature, this material has good biocompatibility. If there is no rejection in the human body, it can be retained in the body for a long time. This material is often used in hip joint replacement and vertebral body replacement, including dental implants.
Jia Jun also introduced that the previous materials include bone cement in orthopedics, allograft bone, etc. These materials have poor biocompatibility, poor molding effect, poor mechanical strength and other characteristics, which can not meet the personalized needs. Now the clinical commonly used is to take the patient's autologous bone, which is bound to bring trauma. At the same time, the requirements for the operation of the doctor are relatively high, and the overall cost of the operation is also high.
华中首例！3D打印钛合金“下颌骨”植入74岁老人面部
Professor Jia Jun checked the patient's CT
The 3D printed titanium alloy prosthesis brings good news to the patient. It does not need to take bone from the human body, where the patient is defective, and what bone needs to be planted, the 3D printed titanium alloy prosthesis can be directly replaced directly, which greatly reduces the patient's pain such as some drug side effects during the operation. For surgeons, because there is no need to perform surgery from the body bone, the entire operation time will be greatly shortened, and there will be a lot of time before the operation to do more accurate and personalized design for the patient.
The tube bed doctor examined Li Lao after the operation.
After the operation, can the patient return to normal function and pre-operative appearance? "This time we just repaired the missing area of the old man's mandible, which is equivalent to the first step of making his appearance symmetrical and supported on both sides, and allowing the teeth on the non-diseased side to achieve normal occlusion. Later, we will also install dentures on his implanted titanium alloy 'mandible bone' to rebuild normal occlusion function." Jia Jun said.
The operation was led by Professor Jia Jun's team from Wuhan University Stomatological Hospital, relying on the national key research and development plan (Chief Scientist: Professor Li Feng) of "Research and Development and Clinical Application of Key Technologies for Additive Manufacturing of Personalized Implant Prostheses for Bone and Joint", and technical assistance was provided by Jia Yi High Tech, Professor Shi Zhiliang's team and Professor Shi Yusheng's team.

Keywords： First case in Central China! 3D printing titanium alloy "mandible" implanted in the face of 74-year-old man

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